Monday, March 13, 2023

Talathi Bharti 4000 पदांच्या तलाठी भरतीला मान्यता नवीन आदेश निर्गमित, पहा सर्व माहिती


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तलाठी भारती 2023 चे शैक्षणिक निकष खाली दिले आहेत, 2023 च्या भरतीच्या नवीनतम पात्रता तपशीलानुसार प्रोसेस तपशील खाली दिले आहेत.
मान्यताप्राप्त शैक्षणिक संस्था किंवा विद्यापीठातून कोणत्याही शाखेतील पदवी.
मराठी, इंग्रजी आणि हिंदी भाषेचे ज्ञान.
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Saturday, November 28, 2020

Immunology 1 Unit MCQ's

 


MCQs On Immunology

1) The branch of biology, which involves the study of immune systems in all organisms is called_________.

(a) Zoology

(b) Microbiology

(c) Immunology

(d) Biotechnology

Sol: (c) Immunology.

2) Which of the following immunity is obtained during a lifetime?

(a) Acquired immunity

(b) Active immunity

(c) Passive immunity

(d) None of the above.

Sol: (a) Acquired immunity

3) How many types of antibodies are there?

(a) Five.

(b) Three.

(c) Two.

(d) Four.

Sol: (a) Five.

4) Which of the following cells is involved in cell-mediated immunity?

(a) Leukaemia

(b) T cells

(c) Mast cells

(d) Thrombocytes

Sol: (b) T cells.

5) Which of the following protects our body against disease-causing pathogens?

(a) Respiratory system

(b) Immune system

(c) Digestive system

(d) Respiratory system

Sol: (b) Immune system.

6) Hepatitis is an example of _______.

(a) Subunit Vaccine

(b) Killer Vaccine

(c) Toxoids Vaccine

(d) Recombinant Vaccine

Sol: (d) Recombinant Vaccine.

7) Which of the following statements is true about the IgM of humans?

(a) IgM can cross the placenta

(b) IgM can protect the mucosal surface

(c) IgM is produced by high-affinity plasma cells

(d) IgM is primarily restricted in the circulation

Sol:(d) IgM is primarily restricted in the circulation.

8) Interferons are

(a) Cytokine barriers

(b) Physical barriers

(c) Cellular barriers

(d) Physiological barriers

Sol: (a) Cytokine barriers.

9) Which of the following cells of the immune system do not perform phagocytosis?

(a) Macrophage

(b) Neutrophil

(c) Eosinophil

(d) Basophil



Sol: (d) Basophil

10) Monocytes differentiate into which kind of phagocytic cells?

(a) Neutrophil

(b) B cell

(c) Macrophge

(d) T cell

Sol: (c) Macrophage.


11. Often patients are immune to diseases like chicken pox once infected. This immunity is an example of
a) Naturally acquired active immunity
b) Artificially acquired active immunity
c) Naturally acquired passive immunity
d) Artificially acquired passive immunity

 

12. Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of

a) Naturally acquired innate immunity
b) Artificially acquired adaptive immunity
c) Naturally acquired passive immunity
d) Artificially acquired passive immunity


Multiple Choice Questions on Immunology - Humoral immunity

1. Humoral immunity is mediated by
a) B cells
b) macrophages
c) both a and b
d) phagocytes
2. Humoral immunity is also called as
a) antibody mediated immunity
b) non-specific immune response
c) antigen mediated immunity
d) all of these

 

3.Any substance that promotes phagocytosis of antigens by binding to them are called as

a) opsonins
b) phagocytes
c) macrophages
d) interleukins

 Answers

1. a) B cells
2. a) antibody mediated immunity

3.a)opsonins


Multiple Choice Questions on Immunology - Complement system

complement system
Complement system
a) consists of 20 serum proteins
b) serum proteins acts as biological cascade
c) both a and b
d) are set of antibodies
2. Complement system is involved in
a) specific defence
b) non-specific defence
c) both a and b
d) none of these
3. Which of the following statements are true regarding complement activation
a) lysis of pathogen, tumor cells and allografts
b) production of mediators that attracts neutrophils to the site of inflammation
c) opsonization
d) all of these
4. Classical pathway of complement system is activated by
a) antibody-antigen complexes
b) antigen
c) antigenic peptides
d) antigens bound to MHC
5. Alternate pathway of complement system is activated by
a) antibody-antigen complexes
b) antigen
c) microorganisms or its toxins
d) antigens bound to MHC
6. Classical pathway of complement system is involved in
a) specific defence
b) adaptive immunity
c) both a and b
d) non-specific defence

 

7. Alternate pathway of complement system is involved in
a) non-specific defence
b) innate immunity
c) both a and b
d) adaptive immunity
8. Which of the following is the central molecule in complement pathway
a) C1
b) C2
c) C3b
d) C5
9. Cell lysis in complement pathway is initiated by
a) membrane destruction complex
b) membrane degradation complex
c) membrane attacking complex
d) membrane lysis complex
10. MAC is
a) C5b6789 complex
b) C5b5678 complex
c) C5b5789 complex
d) Protein polysaccharide complex
11. Which of the following is required for C1 activation
a) Ca
b) Mg
c) Mn
d) Zn
12. Which of the following is the most potent anaphylatoxin
a) C3a
b) C4a
c) C5a
d) C1
13. In alternate pathway
a) factor b is involved
b) factor d is involved
c) both a and b
d) Only factor f is involved
14Biological role of complement system include
a) cytolysis and chemotaxis
b) opsonisation
c) anaphylotoxin and enhanced antibody production
d) all of these
15. Body’s own cells are protected from membrane attack complex by a surface glycoprotein called
a) MHC
b) DAF
c) TCR
d) BCR

 Answers:

1. c) both a and b
2.c) both a and b
3. d) all of these
4. a) antibody-antigen complexes
5. c) microorganisms or its toxins
6. c) both a and b
7. c) both a and b
8. c) C3b
9. c) membrane attacking complex
10. a) C5b6789 complex
11. a) Ca
12. c) C5a.( Anaphylotoxins: induces the release of inflammatory mediators like histamines from the mast cells. C3a, C4a and C5a are the anaphylatoxins of which C5a is the most potent)
13. c) both a and b
14. d) all of these
15. b) DAF (Human cells have a glycoprotein situated on the cell surface called as decay accelerating factor (DAF). DAF prevents the formation of membrane attack complex by destabilizing C3 and C5 convertase.)

Microbiology Questions and Answers – Microbial Flora of Healthy Human Host – Distribution and Occurrence of the Normal Flora

Bacteria can be grown on the dry surface of skin.
a) True
b) False
View Answer

Answer: b
Explanation: The relatively dry surface of the skin is inhibitory to microbial growth. Moist regions of the skin have higher numbers of normal flora.

3. Which of the following causes the disease acne vulgaris?
a) Staphylococcus epidermis
b) Diphtheroids
c) P.acnes
d) E.coli
View Answer

4. Which of the following bacteria are found in the nose?
a) Haemophilus sp.
b) S. pneumoniae
c) Corynebacterium sp.
d) S. epidermidis
View Answer

Answer: d
Explanation: The bacteria most frequently and most consistently found in the nose are S. epidermidis and S. aureus.

5. The microorganisms stick to which of the following regions of the respiratory tract?
a) nasal baffle
b) nasopharynx
c) mucus
d) oropharynx
View Answer

Answer: c
Explanation: Microorganisms will impinge on and stick to the thin moist layer of highly viscous mucus that overlies the surface of the respiratory tract.

6. Alveolar macrophages are phagocytic in nature.
a) True
b) False
View Answer

Answer: a
Explanation: Bacteria that manage to travel the air passages all the way to the alveoli of the lungs are usually engulfed and destroyed by phagocytic body cells known as alveolar macrophages.

7. Saliva generally has a microbial population of _______ bacteria per milliliter.
a) 100
b) 1000
c) 105
d) 108
View Answer

Answer: d
Explanation: Saliva itself generally contains transient microbes from other sites of the oral cavity, particularly from the upper surface of the tongue, and generally has a microbial population of about 108 bacteria per milliliter.

8. Fusobacterium belongs to which type of bacterial group?
a) aerobes
b) facultative anaerobes
c) obligate anaerobes
d) microaerophilic
View Answer

Answer: c
Explanation: As the first teeth appear, obligate anaerobes, such as species of the genera Bacteroides and Fusobacterium, become more evident because the tissue surrounding the teeth provides an anaerobic environment.

Microbiology Questions and Answers – Microbial Flora of Healthy Human Host – Distribution and Occurrence of the Normal Flora

« 
 »

This set of Microbiology online quiz focuses on “Microbial Flora of Healthy Human Host – Distribution and Occurrence of the Normal Flora”.

1. Which of the following viruses are termed as ‘orphan’ viruses?
a) retroviruses
b) echoviruses
c) coxsackieviruses
d) adenoviruses
View Answer

Answer: b
Explanation: Certain human intestinal viruses were discovered only by noting their cytopathogenic effects in tissue cultures; thus they were termed as ‘orphan’ viruses or echoviruses.
2. Bacteria can be grown on the dry surface of skin.a) Trueb) False
View Answer
Answer: b
Explanation: The relatively dry surface of the skin is inhibitory to microbial growth. Moist regions of the skin have higher numbers of normal flora.

3. Which of the following causes the disease acne vulgaris?
a) Staphylococcus epidermis
b) Diphtheroids
c) P.acnes
d) E.coli
View Answer

4. Which of the following bacteria are found in the nose?
a) Haemophilus sp.
b) S. pneumoniae
c) Corynebacterium sp.
d) S. epidermidis
View Answer

Answer: d
Explanation: The bacteria most frequently and most consistently found in the nose are S. epidermidis and S. aureus.

5. The microorganisms stick to which of the following regions of the respiratory tract?
a) nasal baffle
b) nasopharynx
c) mucus
d) oropharynx
View Answer

Answer: c
Explanation: Microorganisms will impinge on and stick to the thin moist layer of highly viscous mucus that overlies the surface of the respiratory tract.

6. Alveolar macrophages are phagocytic in nature.
a) True
b) False
View Answer

Answer: a
Explanation: Bacteria that manage to travel the air passages all the way to the alveoli of the lungs are usually engulfed and destroyed by phagocytic body cells known as alveolar macrophages.

7. Saliva generally has a microbial population of _______ bacteria per milliliter.
a) 100
b) 1000
c) 105
d) 108
View Answer

Answer: d
Explanation: Saliva itself generally contains transient microbes from other sites of the oral cavity, particularly from the upper surface of the tongue, and generally has a microbial population of about 108 bacteria per milliliter.

8. Fusobacterium belongs to which type of bacterial group?
a) aerobes
b) facultative anaerobes
c) obligate anaerobes
d) microaerophilic
View Answer

Answer: c
Explanation: As the first teeth appear, obligate anaerobes, such as species of the genera Bacteroides and Fusobacterium, become more evident because the tissue surrounding the teeth provides an anaerobic environment.

9. Which enzyme is required for the production of glucan?
a) glycosyl transferase
b) glucoisomerase
c) hexokinase
d) glucose-6-phosphatase
View Answer


10. Enterococci is found in which part of the intestine?
a) duodenum
b) jejunum
c) ileum
d) large intestine
View Answer

Answer: b
Explanation: In the jejunum there are occasionally found species of enterococci, lactobacilli, and diphtheroids.

11. Which body part contains the largest microbial population?
a) stomach
b) small intestine
c) large intestine
d) mouth
View Answer

Answer: c
Explanation: In the human body the colon or large intestine has the largest microbial population. It has been estimated that the number of microorganisms in stool specimens is about 1011 organisms per gram wet weight.

12.Which of the following is not a Gram-positive bacilli?
a) Bacteroides
b) Eubacterium
c) Lactobacillus
d) Bifidobacterium
View Answer

Answer: a
Explanation: The Gram-positive bacilli are represented mainly by species of Bifidobacterium, Eubacterium, and Lactobacillus. But Bacteroides are anaerobic Gram-negative bacilli.

13.Which microorganism among the following can live as a commensal but can also be pathogenic?
a) Trichomonas hominis
b) Entamoeba histolytica
c) Endolimax
d) Iodamoeba
View Answer

Answer: b
Explanation: Entamoeba histolytica can live as a commensal but can also be pathogenic, causing amoebic dysentery; it is capable of penetrating the intestinal mucosa and invading various organs of the body.

14.Tuberculosis is which type of infection?
a) acute
b) chronic
c) primary
d) secondary
View Answer

Answer: b
Explanation: Chronic infections are those diseases which has a long duration like tuberculosis disease.

15.Where does Streptococcus pyogenes infects in the body to cause infection?
a) cervix
b) small intestine
c) urethra
d) throat
View Answer

Answer: d
Explanation: Streptococcus pyogenes, the causative agent of streptococcal sore throat, attaches specifically to the epithelial cells of the throat by means of cell wall proteins.

16.In which of the following body part does the influenza virus does not penetrate?
a) small intestine
b) nasopharynx
c) trachea
d) bronchi
View Answer

Answer: a
Explanation: The influenza virus penetrates the epithelial cells lining the nasopharynx, trachea and bronchi.

17.Which of the following is an arthropod?
a) Clostridium perfringens
b) Borrelia sp.
c) Shigella
d) Pseudomonas aeruginosa
View Answer

Answer: b
Explanation: Arthropods follow passive penetration such as that by Borrelia species which causes relapsing fever in humans.

Life Sciences Questions and Answers – Immunology Introduction

« 
 »

This set of Life Sciences Multiple Choice Questions & Answers (MCQs) focuses on “Immunology Introduction”.

1. The ability of an organism to resist infections by the pathogens is called___________
a) Infection
b) Hypersensitivity
c) Immunity
d) Allergy
View Answer

Answer: c
Explanation: Immunity is the ability of an organism to resist infections with the help of the immune system. Immunity is further divided into two categories, i.e. innate immunity and adaptive immunity.

2. Innate immunity present since birth and it has no memory.
a) True
b) False
View Answer

Answer: a
Explanation: Innate immunity is the natural immunity, which is present for the birth and it operated against any foreign molecules and pathogens. It provides the first line of defense and is not specific in nature.

3. Which of the following compounds is NOT found in tears?
a) Lysozyme
b) Lactoferin
c) IgA
d) IgE
View Answer

Answer: d
Explanation: IgE participates in hypersensitivity reactions, but not present in tears. Tears are the secretion of lacrimal gland and also know as lacrimal fluid consists of lysozyme, lactoferrin, and IgA.

4. Name the cytokines which released in response to virus infection?
a) Interferons
b) Monokines
c) Lymphokines
d) Interleukins
View Answer

Answer: a
Explanation: Monokines, lymphokines, interleukins, and interferons are cytokines which are of low molecular weight soluble protein or glycoprotein. Interferon is cytokines produced by cells in response to virus infections.

5. Name the group of pattern recognition molecules which functions exclusively as a signaling receptor?
a) CRP
b) Toll-like receptor
c) MBL
d) LPS
View Answer

Answer: b
Explanation: Toll-like receptor functions exclusively as a signaling receptor and is a pattern recognition molecule. It was identified as a protein involved in the formation of dorso-ventral polarity in developing fly embryos.

6. Name the first cell which recruited at the place of infection.
a) Nk cells
b) Basophils
c) Nutrophils
d) Macrophages
View Answer

Answer: c
Explanation: Neutrophils are second major type of phagocytic cell which is found in abundance in blood and have short life span.

7. Name the nerve stimulator which is responsible for the pain of the inflammation.
a) Bradikinins
b) Prostaglandin
c) Histamines
d) Kinins
View Answer

Answer: d
Explanation: Kinins are the principal mediator of inflammatory response which is present in blood plasma in an inactive form. It causes vasodilation and increased permeability of capillaries.

8. Which of the following is NOT the characteristics of a good antigen.
a) Large in size
b) Foreignness
c) Highly complex
d) Reproduce only by binary fission
View Answer

Answer: d
Explanation: A good antigen is defined by its complexity and size, plus its foreignness and dosage. Large size and highly complex antigen are considered as good and more responsive.

9. Which of the following antibody gives a primary immune reaction?
a) IgG
b) IgM
c) IgA
d) IgE
View Answer

Answer: b
Explanation: The first class of antibody which provide a primary immune response is IgM followed by IgG. When the same antigen attack again, the secondary immune response generated which is provided by IgG.
1.Immunity acquired after an infection is
(a) active immunity
(b) Passive immunity
(c) Innate immunity
(d) Both B and C
Answer: (a)
2.Immunological destruction of body tissue or product due to antibodies reacting with it as antigen is called
(a) Anaphylaxis
(b) Autoimmune diseases
(c) Prophylaxis
(d) Immunodeficiency disease
Answer: (b)
3.Increased asthmatic attacks in certain seasons are due to
(a) Inhalation of seasonal pollen
(b) Heat and humidity
(c) Low temperature
(d) Eating preserved fruits
Answer: (a)
4.Inflammation reaction is brought about by
(a) Plasma cells
(b) Mast cells
(c) Macrophages
(d) Adipose cells
Answer: (b)
5.Inflammatory response in allergy is due to release by mast cells of
(a) Antibodies
(b) Antigens
(c) Histamine
(d) All the above
Answer: (c)
6.Innate immunity is
(a) Active acquired immunity
(b) Passive acquired immunity
(c) Inborn immunity
(d) Both B and C
Answer: (c)
7.Innate immunity is provided by
(a) Phagocytes
(b) Antibodies
(c) T-Lymphocytes
(d) B-Lymphocytes
Answer: (a)
8.Which one engulfs foreign materials
(a) Macrophages
(b) Plasma cells
(c) Mast cells
(d) Lymphocytes
Answer: (a)
9.Macrophages are derived from
(a) Neutrophils
(b) Lymphocytes
(c) Monocytes
(d) Basophils
Answer: (c)
10.Meory cells are formed from
(a) Erythropoietic stem cells
(b) Monocytes
(c) T-lymphocytes
(d) B-lymphocytes
Answer: (d)
11.O blood group is universal donor because the blood has
(a) Antigen A
(b) Antigen B
(c) Both antigens A and B
(d) No antigens
Answer: (d)
12.Passive immunity is
(a) Acquired through natural overt or latent infection
(b) Acquired through Vaccination
(c) Acquired through readymade antibodies
(d) Acquired by activating immune system of the body
Answer: (c)
13.Which one helps in differentiation of cells of immune system
(a) Cortiosol
(b) Thymosin
(c) Steroid
(d) Thyroxine.
Answer: (b)
14.Passive immunity is obtained through injecting
(a) Antibiotics
(b) Vaccines
(c) Antibodies
(d) Antigens
Answer: (c)
15.Persons with blood group A posses
(a) Antigen A and antibodies b
(b) Antigen A and antibodies a
(c) No antigen but antibodies aand b
(d) antigens A and B but no antobodies
Answer: (a)
16.Progenitors formed in bone marrow but differentiating elsewhere are
(a) Pre-NK cells
(b) Pre-erythroblasts
(c) Pre-T cells
(d) Myeloblasts
Answer: (c)
17.Resistance developed in an individual as a result of antigenic stimulus is
(a) Natural immunity
(b) Active acquired immunity
(c) Passive acquired immunity
(d) Artificial immunity
Answer: (b)
18.Rh-  mother carries Rh+ foetus. The foetus is at a risk of disease called
(a) Haemophilia
(b) Haemolytic disease
(c) Tuberculosis
(d) Syphilis
Answer: (b)
19.Rh factor is named after
(a) Monkey
(b) Drosphila
(c) Rat
(d) Man
Answer: (a)
20.Segments of antigen that are recognized by antibody are
(a) Memory regions
(b) Epitopes
(c) Nondeterminants
(d) Self limitation
Answer: (b)